Implants are used in a variety of medical applications, such as Orthopedics, Spine surgery, Cardio vascular, Dental, and others. Wettability/hydrophilicity is a key feature of metal implants, improving implant osseointegration and long-term stability. Plasma is well known for its surface activation properties, but the hydrophilic properties of implants tend to deteriorate between manufacturing date and the actual time of implantation.
Nova’s Active+ Plasma Capsule
Nova Plasma solves this problem with a new concept – The Active+ Plasma Capsule. The implant comes in a pre-packed disposable capsule, sealed and sterilized at the factory. In the operating room or clinic, the capsule is plugged into a desktop unit which activates the plasma process, surface treating the implant. After 30 sec the capsule is opened and the super hydrophilic and super clean implant is ready for implantation.
TheMarker / Biomed edition 24.05.2016- The Next Generation of Medical Implants
An innovative platform technology enables surface modification of medical implants right before implantation, and improves the success rate / Nimrod Gazit
Nova plasma was formed in 2012 by Chen Porat, Amnon Ronen Lam – three entrepreneurs with extensive experience in the building, development and commercialization of start-up companies. The company is developing a unique and innovative platform technology, which enables the surface modification of implantable devices, via cold plasma, on-site, just prior to implantation.
Plasma Treatment Maintains Surface Energy of the Implant Surface and Enhances Osseointegration
In this study, 2 surfaces: nonwashed resorbable blasting media and Ar-based nonthermal plasma 30 days were investigated with a focus on the surface energy. Five adult beagle dogs received 8 implants. After 2 weeks, the animals were euthanized, and half of the implants were removal torqued and the other half were histologically processed. The bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated on the histologic sections.
Atmospheric plasma enhances wettability and cell spreading on dental implant metals.
In this study, a cold atmospheric pressure gas-discharge plasma was applied to reduce water contact angles on titanium discs with different surface topography and to improve the spreading of osteoblastic cells.
Contact angle was significantly reduced close to 0° irrespective of surface topography after the application of argon plasma with 1.0% oxygen admixture for 60 / 120 sec. The cell size of osteoblastic cells grown on argon-oxygen-plasma-treated titanium discs was significantly larger than on non-treated surfaces (p < 0.001) irrespective of surface topography.